9 (E),11 (E) -12-nitro Conjugated Linoleic Acid

9 (E),11 (E) -12-nitro Conjugated linoleic acid (9 (E),11 (E) -12-nitro CLA) is a nitrated fatty acid. It is formed from 9 (Z),11 (E) -CLA upon exposure to acidified nitrite, peroxynitrite, gaseous nitrogen dioxide, or a combination of myeloperoxidase, hydrogen peroxide, and nitrite.1It is also formed in LPS-stimulated RAW 264.7 macrophages, an effect that can be reduced by the nitric oxide synthase (NOS) inhibitor L-NAME .29 (E),11 (E) -12-nitro CLA has been found in human plasma.