(±) 8,9-DiHETE
Product Specifications
CAS Number
867350-87-6
Target
Others
Related Pathways
Others
Bioactivity
(±) 8,9-DiHETE is a major metabolite of the 20:5 ω-3 fatty acid eicosapentaenoic acid .[1] It is produced in rat liver microsomes, but not renal microsomes, by the generation of the unstable intermediate 8,9-epoxy eicosatetraenoic acid from EPA by cytochrome P450 monooxygenases. Dietary EPA supplementation in humans results in substantial urinary excretion of vicinal diols, including 8,9, 11,12, and 14,15 forms.[2]
Smiles
CC\C=C/C\C=C/C\C=C/CC(O)C(O)C\C=C/CCCC(O)=O
Molecular Formula
C20H32O4
Molecular Weight
336.472
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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