CC4
Product Specifications
CAS Number
492-02-4
Target
Others, AChR
Related Pathways
Neuroscience, Others
Bioactivity
High affinity and subtype selective α6β2 and α4β2 partial agonist (Ki values are 12 and 26nM for rat α6β2 and α4β2 receptors respectively) . Has low affinity for α3β4 and α7 receptors (Ki values are 4.8 and 13 μM for human α3β4 and rat α7 receptors respectively) . Stimulates dopamine release from striatal slices in vitro. Attenuates nicotine-induced self-administration and conditional place preference in rats.
Smiles
O=c1cccc2C3C[C@@H](CN(CCN4C[C@@H]5CC(C4)c4cccc(=O)n4C5)C3)Cn12
Molecular Formula
C24H30N4O2
Molecular Weight
406.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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