CC4
Product Specifications
CAS Number
492-02-4
Target
Others|||AChR
Related Pathways
Neuroscience|||Others
Bioactivity
High affinity and subtype selective ?6?2 and ?4?2 partial agonist (Ki values are 12 and 26nM for rat ?6?2 and ?4?2 receptors respectively) . Has low affinity for ?3?4 and ?7 receptors (Ki values are 4.8 and 13 ?M for human ?3?4 and rat ?7 receptors respectively) . Stimulates dopamine release from striatal slices in vitro. Attenuates nicotine-induced self-administration and conditional place preference in rats.
Smiles
O=c1cccc2C3C[C@@H](CN(CCN4C[C@@H]5CC(C4)c4cccc(=O)n4C5)C3)Cn12
Molecular Formula
C24H30N4O2
Molecular Weight
406.52
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Curated Selection
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