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BTC AM

Product Specifications

CAS Number

176767-94-5

Target

Others

Related Pathways

Others

Bioactivity

BTC AM is a cell-permeable acetoxy-methyl ester of BTC . As BTC AM enters cells, it is hydrolyzed by intracellular esterases to produce BTC. BTC is a low affinity calcium indicator (Kd = 7-26 μM) that displays excitation/emission spectra of 401/529 nm, respectively. It exhibits a shift in the excitation maximum from approximately 480 to 401 nm upon calcium binding, enabling determination of ratiometric calcium measurements. BTC is suitable for detecting elevated calcium levels associated with activation of smooth muscle, neurons, and intracellular calcium stores.

Smiles

O=C1OC2=CC(=C(OCCOC3=CC(=CC=C3N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C)C)C=C2C=C1C4=NC=5C=CC=CC5S4)N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C

Molecular Formula

C45H45N3O20S

Molecular Weight

979.91

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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