SARS-CoV MPro-IN-1
Product Specifications
CAS Number
2413716-71-7
Target
Others, SARS-CoV
Related Pathways
Microbiology/Virology, Others
Bioactivity
MProinhibitor 11b is an inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (MPro; IC50= 0.04 μM in a TR-FRET assay) .1It reduces viral yield in the culture supernatant of SARS-CoV-2-infected Vero E6 cells (EC50= 0.72 μM) . MProinhibitor 11b also reduces viral RNA copy numbers in the same model when used at concentrations ranging from 1.85 to 50 μM.
Smiles
C(N[C@@H](CC1=CC(F)=CC=C1)C(N[C@@H](C[C@H]2C(=O)NCC2)C=O)=O)(=O)C3=CC=4C(N3)=CC=CC4
Molecular Formula
C25H25FN4O4
Molecular Weight
464.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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