8 (S) -HETE
Product Specifications
CAS Number
98462-03-4
Target
Others, PPAR
Related Pathways
Others, Metabolism, DNA Damage/DNA Repair
Bioactivity
8 (S) -HETE, a major lipoxygenase product in PMA-treated murine epidermis, activates mouse keratinocyte protein kinase C with an IC50 of 100 μM and selectively activates PPARα at concentrations as low as 0.3 μM. The stereochemical assignment of the (S) enantiomer is based on comparison of chiral HPLC retention times to published results.
Smiles
[C@H](C/C=C\CCCC(O)=O)(/C=C/C=C\C/C=C\CCCCC)O
Molecular Formula
C20H32O3
Molecular Weight
320.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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