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BAY-876

Product Specifications

CAS Number

1799753-84-6

Target

Transporter

Related Pathways

Metabolism

Purity

0.9978

Bioactivity

BAY-876 is an orally active, selective inhibitor of glucose transporter 1 (GLUT1, IC50= 2 nM), exhibiting over 130-fold greater selectivity for GLUT1 than GLUT2, GLUT3, and GLUT4. It also inhibits glycolytic metabolism and ovarian cancer growth.

Smiles

Cc1c(NC(=O)c2cc(nc3cc(F)ccc23)C(N)=O)c(nn1Cc1ccc(cc1)C#N)C(F)(F)F

Molecular Formula

C24H16F4N6O2

Molecular Weight

496.42

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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