(Z) -4EGI-1
Product Specifications
CAS Number
901787-88-0
Target
Others|||PERK
Related Pathways
Apoptosis|||Others
Bioactivity
(Z) -4EGI-1, the Z-isomer of 4EGI-1, serves as an inhibitor of both the eIF4E/eIF4G interaction and translation initiation. It effectively binds to eIF4E, exhibiting an IC50 of 43.5 ?M and a Kd value of 8.74 ?M. Notably, (Z) -4EGI-1 possesses anticancer activity[1][2].
Smiles
N(/N=C(/CC1=C(N(=O)=O)C=CC=C1)\C(O)=O)C2=NC(=CS2)C3=CC(Cl)=C(Cl)C=C3
Molecular Formula
C18H12Cl2N4O4S
Molecular Weight
451.28
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15292366 1 Vial
Lentiviral mouse Tia1 shRNA (UAS) - Lentiviral mouse Tia1 shRNA (UAS, GFP) plasmid
Ask
View Details ![Human Monoclonal EGFR Antibody (Hu104) [PE]](https://cdn.genprice.uk/genprice/uk/genprice5.webp)
AP2C968-01 1 mg
Recombinant Mouse Interleukin-3 Receptor Subunit Alpha (IL-3RA), C-Fc
Ask
View Details AP2C968-02 10 µg
Recombinant Mouse Interleukin-3 Receptor Subunit Alpha (IL-3RA), C-Fc
Ask
View Details