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HS271

Product Specifications

CAS Number

2410393-15-4

Target

IRAK

Related Pathways

NF-κB, Immunology/Inflammation

Purity

0.9879

Bioactivity

HS271 is a selective, highly potent and orally active IRAK4 inhibitor (IC50= 7.2 μM) . HS271 shows excellent enzymatic and cellular activities, as well as excellent pharmacokinetic properties.

Smiles

CN(C)CCn1cc2cc(NC(=O)c3cccc(n3)C(F)(F)F)c(cc2n1)C(C)(C)O

Molecular Formula

C21H24F3N5O2

Molecular Weight

435.44

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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