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CB2R PAM

Product Specifications

CAS Number

2244579-87-9

Target

Cannabinoid Receptor

Related Pathways

GPCR/G Protein

Purity

0.9909

Bioactivity

CB2R PAM is an orally active cannabinoid type 2 receptor (CB2Rs) positive allosteric modulator that enhances CP 55940 and 2-Arachidonylglycerol-stimulated [35S]GTP?S binding to CB2 receptors without affecting receptor activity in the absence of agonists. CB2R PAM shows anti-injury activity in a mouse model of neuropathic pain.

Smiles

N(C(=O)C1CCCCCC1)C=2C(=O)N(CC3=CC=C(F)C=C3)C=C(Br)C2C

Molecular Formula

C21H24BrFN2O2

Molecular Weight

435.33

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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