What is the catalog number for MD-222?

The catalog number for MD-222 is T37041.

What sizes are available for MD-222?

MD-222 is available in the following size(s): 5 mg, 10 mg, 25 mg.

How many pack sizes does MD-222 come in?

MD-222 is available in 3 different pack sizes.

MD-222 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MD-222?

MD-222 is manufactured by Molfinity.

What is the estimated delivery time for MD-222?

Estimated delivery time for MD-222 is approximately 10 business day(s), depending on your location.

MD-222

Product Specifications

CAS Number

2136246-72-3

Target

MDM-2/p53, PROTACs, E1/E2/E3 Enzyme

Related Pathways

Apoptosis, PROTAC, Ubiquitination

Bioactivity

MD-222, a pioneering, highly potent PROTAC degrader targeting MDM2, efficiently mediates the rapid degradation of MDM2 protein and activates wild-type p53 within cells, showcasing significant anticancer effects[1][2].

Smiles

Fc1c(Cl)cccc1[C@H]1[C@@H](NC2(CCCCC2)[C@@]11C(=O)Nc2cc(Cl)ccc12)C(=O)Nc1ccc(cc1)C(=O)NCCCCCc1cccc2C(=O)N(Cc12)C1CCC(=O)NC1=O

Molecular Formula

C48H47Cl2FN6O6

Molecular Weight

893.84

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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