MD-222

Product Specifications

CAS Number

2136246-72-3

Target

MDM-2/p53|||PROTACs|||E1/E2/E3 Enzyme

Related Pathways

Apoptosis|||PROTAC|||Ubiquitination

Bioactivity

MD-222, a pioneering, highly potent PROTAC degrader targeting MDM2, efficiently mediates the rapid degradation of MDM2 protein and activates wild-type p53 within cells, showcasing significant anticancer effects[1][2].

Smiles

Fc1c(Cl)cccc1[C@H]1[C@@H](NC2(CCCCC2)[C@@]11C(=O)Nc2cc(Cl)ccc12)C(=O)Nc1ccc(cc1)C(=O)NCCCCCc1cccc2C(=O)N(Cc12)C1CCC(=O)NC1=O

Molecular Formula

C48H47Cl2FN6O6

Molecular Weight

893.84

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MF-0048361 5 mg

Daphnicyclidin F

Ask

View Details

TL707302V 500 µL Each

Pgm3 Rat shRNA Lentiviral Particle (Locus ID 363109)

Ask

View Details

NBP1-49311JF646 0.1 mL

Mouse Monoclonal CLEC4E Antibody (16E3) [Janelia Fluor 646]

Ask

View Details

HP216292 200 Reactions

KRTAP4-11 Human qPCR Primer Pair (NM_033059)

Ask

View Details

TP302003M 100 µg

FE65 (APBB1) (NM_001164) Human Recombinant Protein

Ask

View Details

MP0628J Each

Magic™ Membrane Protein Human CCL5 (C-C motif chemokine ligand 5) for Antibody Discovery

Ask

View Details