Mca-PLAC (p-OMeBz) -WAR (Dpa) -NH2
Product Specifications
CAS Number
1926163-82-7
Target
Others, MMP
Related Pathways
Proteases/Proteasome, Others
Bioactivity
Mca-PLAC (p-OMeBz) -WAR (Dpa) -NH2 is a fluorogenic substrate for matrix metalloproteinase-14 (MMP-14) . Upon cleavage by MMP-14, 7-methoxycoumarin-4-acetyl (Mca) is released and its fluorescence can be used to quantify MMP activity. Mca displays excitation/emission maxima of 328/420 nm, respectively.
Smiles
C(C(=O)N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC=2C=3C(NC2)=CC=CC3)C(N[C@H](C(N[C@H](C(N[C@@H](CNC4=C(N(=O)=O)C=C(N(=O)=O)C=C4)C(N)=O)=O)CCCNC(=N)N)=O)C)=O)=O)CSCC5=CC=C(OC)C=C5)=O)C)=O)CC(C)C)=O)CCC1)C=6C=7C(=CC(OC)=CC7)OC(=O)C6
Molecular Formula
C66H82N16O17S
Molecular Weight
1403.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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