Previridicatumtoxin
Product Specifications
CAS Number
1379585-81-5
Target
Others|||Endogenous Metabolite|||Antibacterial
Related Pathways
Metabolism|||Microbiology/Virology|||Others
Bioactivity
Previridicatumtoxin is a fungal metabolite that has been found inP. aethiopicumand has diverse biological activities.1,2It is an intermediate in the biosynthesis of the mycotoxin viridicatumtoxin . Previridicatumtoxin is active against methicillin-resistantS. aureus (MRSA) and vancomycin-resistantE. faecalis (IC50s = 4.4 and 4.8 ?M, respectively), as well asC. albicansandS. cerevisiae (MIC = 32 ?g/ml for both) .2,1It is cytotoxic to NCI H460, KB-3-1, and SW620 cancer cells (IC50s = 5.3, 4.1, and 6 ?M, respectively) .2
Smiles
COc1cc(O)c2c(O)c3C(=O)C4(O)C(=O)C(C(N)=O)=C(O)CC4(O)C(O)c3c(C\C=C(/C)CCC=C(C)C)c2c1
Molecular Formula
C30H33NO10
Molecular Weight
567.58
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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