Estriol 3-β-D-Glucuronide (sodium salt)
Product Specifications
CAS Number
15087-06-6
Target
Others, Endogenous Metabolite
Related Pathways
Others, Metabolism
Bioactivity
Estriol 3-β-D-glucuronide is a metabolite of estriol . It is formed from estriol by the UDP-glucuronosyltransferase (UGT) isoform UGT1A10. Estriol 3-β-D-glucuronide binds to basolateral and canalicular liver plasma membranes with Kd values of 85 and 164 μM, respectively. It competitively inhibits the hydrolysis of 4-methylumbelliferyl-β-D-glucuronide and is a substrate for hydrolysis by Klotho-human IgG1 Fc protein (KLFc) .
Smiles
[Na].[H][C@@]12C[C@@H](O)[C@H](O)[C@@]1(C)CC[C@]1([H])c3ccc(O[C@@H]4O[C@@H]([C@@H](O)[C@H](O)[C@H]4O)C(O)=O)cc3CC[C@@]21[H]
Molecular Formula
C24H31NaO9
Molecular Weight
486.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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