SCH900776 (S-isomer)

Product Specifications

CAS Number

891494-64-7

Target

CDK|||Chk|||Others

Related Pathways

Cell Cycle/Checkpoint|||Others

Purity

0.9995

Bioactivity

SCH900776 S-isomer (MK-8776 S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM) . It also inhibitors Chk2 (IC50: 1500 nM) and cyclin-dependent kinase CDK2 (IC50: 160 nM) .

Smiles

Cn1cc(cn1)-c1cnn2c(N)c(Br)c(nc12)[C@H]1CCCNC1

Molecular Formula

C15H18BrN7

Molecular Weight

376.25

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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