MSA-2 dimer
Product Specifications
CAS Number
2377881-92-8
Target
Others|||STING
Related Pathways
Immunology/Inflammation|||Others
Bioactivity
MSA-2 dimer, a selective and orally active non-nucleotide STING agonist with a dissociation constant (Kd) of 145 ?M, demonstrates prolonged antitumor and immunogenic activity. It non-covalently binds to STING as a dimer, showing greater permeability compared to cyclic dinucleotide[1].
Smiles
COc1cc2sc(cc2cc1CCCc1cc2cc(sc2cc1OC)C(=O)CCC(O)=O)C(=O)CCC(O)=O
Molecular Formula
C29H28O8S2
Molecular Weight
568.66
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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