GSK 591 dihydrochloride
Product Specifications
CAS Number
2320953-89-5
Target
Others, Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic, Others
Bioactivity
Potent and selective PRMT5 inhibitor (IC50 = 4 nM) . Selective for PRMT5 over a panel of other PRMTs and lysine methyltransferases. Inhibits proliferation of mantle cell lymphoma (MCL) in vitro. To request the negative control for GSK 591, please fill out the SGC 2096 request form on the SGC website.
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Cl.Cl.O[C@@H](CNC(=O)c1ccnc(NC2CCC2)c1)CN1CCc2ccccc2C1
Molecular Formula
C22H30Cl2N4O2
Molecular Weight
453.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Frequently Asked Questions
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