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LSN3106729 hydrochloride

Product Specifications

CAS Number

2704316-82-3

Target

Others, Ligands for Target Protein for PROTAC, CDK

Related Pathways

PROTAC, Others, Cell Cycle/Checkpoint

Bioactivity

LSN3106729 hydrochloride, the metabolite of Abemaciclib , is a CDK inhibitor with antitumor activity. LSN3106729 hydrochloride and a CRBN ligand have been used to design PROTAC CDK4/6 degrader[1].

Smiles

Cl.FC=1C=NC(=NC1C=2C=C(F)C=3N=C(N(C3C2)C(C)C)CO)NC4=NC=C(C=C4)CN5CCNCC5

Molecular Formula

C25H29ClF2N8O

Molecular Weight

531

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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