LSN3106729 hydrochloride
Product Specifications
CAS Number
2704316-82-3
Target
Others, Ligands for Target Protein for PROTAC, CDK
Related Pathways
PROTAC, Others, Cell Cycle/Checkpoint
Bioactivity
LSN3106729 hydrochloride, the metabolite of Abemaciclib , is a CDK inhibitor with antitumor activity. LSN3106729 hydrochloride and a CRBN ligand have been used to design PROTAC CDK4/6 degrader[1].
Smiles
Cl.FC=1C=NC(=NC1C=2C=C(F)C=3N=C(N(C3C2)C(C)C)CO)NC4=NC=C(C=C4)CN5CCNCC5
Molecular Formula
C25H29ClF2N8O
Molecular Weight
531
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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