Aminopeptidase N Inhibitor
Product Specifications
CAS Number
596108-59-7
Target
Others, Aminopeptidase
Related Pathways
Metabolism, Others
Bioactivity
Aminopeptidase N (AP-N) inhibitor is a reversible inhibitor of AP-N/CD13 (IC50 = 25 μM) . It is selective for AP-N/CD13 over matrix metalloproteinase-9 (MMP-9), angiotensin converting enzyme (ACE), neutral endopeptidase (NEP), γ-glutamyl transpeptidase, and the serine proteases dipeptidyl peptidase 4 (DPP-4) and cathepsin G at a concentration of 1 mM. AP-N inhibitor is non-cytotoxic to U937 cells at a concentration of 100 μM.
Smiles
N(=O)(=O)C1=C(OC=2C(C1=O)=CC=CC2CC(O)=O)C3=C(N(=O)=O)C=CC=C3
Molecular Formula
C17H10N2O8
Molecular Weight
370.27
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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