CXCR2-IN-2
Product Specifications
CAS Number
1838123-21-9
Target
CXCR
Related Pathways
Autophagy, GPCR/G Protein, Immunology/Inflammation
Bioactivity
CXCR2-IN-2 (compound 68) is a highly selective CXCR2 antagonist (IC50=5.2 nM) with the advantages of blood-brain barrier penetration and oral bioavailability. It inhibits Gro-α-induced CD11b expression in human whole blood (IC50=0.04 μM) .
Smiles
S(=O)(=O)(C1=C(O)C(NC(N[C@H]2C(C)=CCC2)=O)=CC=C1Cl)[C@@]3(C)CCOC3
Molecular Formula
C18H23ClN2O5S
Molecular Weight
414.9
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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