A-740003
Product Specifications
CAS Number
861393-28-4
Target
P2X Receptor
Related Pathways
Neuroscience, Membrane transporter/Ion channel
Purity
0.9968
Bioactivity
A-740003 (A 740003) is an effective and specific P2X7 receptor antagonist (IC50: 18/40 nM, for rat/human) . It can reduce nociception in animal models of persistent neuropathic and inflammatory pain, and also reduce neuroblastoma tumor growth in mice.
Smiles
COc1ccc(CC(=O)NC(N\C(Nc2cccc3ncccc23)=N\C#N)C(C)(C)C)cc1OC
Molecular Formula
C26H30N6O3
Molecular Weight
474.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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