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A-740003

Product Specifications

CAS Number

861393-28-4

Target

P2X Receptor

Related Pathways

Neuroscience, Membrane transporter/Ion channel

Purity

0.9968

Bioactivity

A-740003 (A 740003) is an effective and specific P2X7 receptor antagonist (IC50: 18/40 nM, for rat/human) . It can reduce nociception in animal models of persistent neuropathic and inflammatory pain, and also reduce neuroblastoma tumor growth in mice.

Smiles

COc1ccc(CC(=O)NC(N\C(Nc2cccc3ncccc23)=N\C#N)C(C)(C)C)cc1OC

Molecular Formula

C26H30N6O3

Molecular Weight

474.55

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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