MRIA9
Product Specifications
CAS Number
2750707-05-0
Target
Others, PAK, Apoptosis, SIK
Related Pathways
Apoptosis, PI3K/Akt/mTOR signaling, Others, Cytoskeletal Signaling
Bioactivity
MRIA9, an ATP-competitive inhibitor targeting pan Salt-Inducible Kinases (SIK) and PAK2/3, demonstrates IC50 values of 516 nM, 180 nM, and 127 nM for SIK1, SIK2, and SIK3, respectively [1].
Smiles
C(N1C=2C(C=C(C1=O)C3=C(Cl)C=C(C=C3)C4=C(F)C=CC=N4)=CN=C(NC)N2)[C@@H]5OC[C@@H](N)CO5
Molecular Formula
C24H22ClFN6O3
Molecular Weight
496.92
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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