What is the catalog number for BM-1244?

The catalog number for BM-1244 is T36884.

What sizes are available for BM-1244?

BM-1244 is available in the following size(s): 10 mg, 5 mg, 25 mg.

How many pack sizes does BM-1244 come in?

BM-1244 is available in 3 different pack sizes.

BM-1244 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures BM-1244?

BM-1244 is manufactured by Molfinity.

What is the estimated delivery time for BM-1244?

Estimated delivery time for BM-1244 is approximately 10 business day(s), depending on your location.

BM-1244

Product Specifications

CAS Number

1619923-32-8

Target

Others, Apoptosis, PARP, Bcl-2 Family, Caspase

Related Pathways

Others, Proteases/Proteasome, DNA Damage/DNA Repair, Apoptosis, Chromatin/Epigenetic

Bioactivity

BM-1244 is a potent Bcl-xL/Bcl-2 inhibitor with Kis of 134 and 450 nM for Bcl- xL and Bcl-2, respectively. BM-1244 inhibits senescent fibroblasts (SnCs) with an EC50 of 5 nM[1].

Smiles

CC(C)n1c(C)c(c(c1-c1ccc(Cl)cc1)-c1cc(F)cc(c1)N1CCN(CC1)c1ccc(NS(=O)(=O)c2ccc(N[C@H](CCN3CCC(CC3)C(O)=O)CSc3ccccc3)c(c2)S(=O)(=O)C(F)(F)F)cc1)S(C)(=O)=O