Sclerotiorin
Product Specifications
CAS Number
549-23-5
Target
Others, Lipoxygenase, Antifungal
Related Pathways
Metabolism, Microbiology/Virology, Others
Bioactivity
Sclerotiorin is a natural product isolated primarily from Penicillium species. It inhibits soybean lipoxygenase-1 with an IC50 value of 4.2 μM. Sclerotiorin also exhibits a number of other activities including inhibition of cholesterol ester transfer protein (IC50 = 19.4 μM), , inhibition of Grb2-Shc interaction (IC50 = 22 μM), , and antagonism of endothelin receptors (IC50 = 114 and 152 μM for human ETA and ETB, respectively) .
Smiles
O=C1C=2C(=C(Cl)C(=O)[C@@]1(OC(C)=O)C)C=C(/C=C/C(=C/[C@H](CC)C)/C)OC2
Molecular Formula
C21H23ClO5
Molecular Weight
390.86
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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