5-Octyl-?-ketoglutarate
Product Specifications
CAS Number
1616344-00-3
Target
Others|||Histone Methyltransferase|||E1/E2/E3 Enzyme
Related Pathways
Ubiquitination|||Chromatin/Epigenetic|||Others
Bioactivity
In addition to its role in the Krebs cycle, ?-ketoglutarate (2-oxoglutarate) has roles as a substrate or modulator of enzymes. 5-Octyl-?-ketoglutarate, also known as ?-ketoglutarate octyl ester, is a stable, cell-permeable molecule that generates free ?-ketoglutarate upon hydrolysis of the ester bond by cytoplasmic esterases. It is used in experiments to increase levels of intracellular ?-ketoglutarate. 5-Octyl-?-ketoglutarate has been shown to modulate a variety of enzymes and signaling pathways, particularly in the context of glycolysis, hypoxia, and cancer.
Smiles
C(C(OCCCCCCCC)=O)CC(C(O)=O)=O
Molecular Formula
C13H22O5
Molecular Weight
258.31
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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