Combretastatin A-1
Product Specifications
CAS Number
109971-63-3
Target
Akt|||Microtubule Associated|||Wnt/beta-catenin
Related Pathways
Cytoskeletal Signaling|||Stem Cells|||PI3K/Akt/mTOR signaling
Purity
0.9749
Bioactivity
Combretastatin A-1 is a potent microtubule inhibitor with anti-tumour and anti-vascular activity, acting through microtubule protein depolymerisation-mediated inactivation of AKT to inhibit the Wnt/?-catenin pathway, and can be used to study hepatocellular carcinoma.
Smiles
COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)c(O)c1O
Molecular Formula
C18H20O6
Molecular Weight
332.35
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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