Ac-FLTD-CMK
Product Specifications
Target
Pyroptosis|||Caspase
Related Pathways
Immunology/Inflammation|||Apoptosis|||Proteases/Proteasome
Purity
0.9861
Bioactivity
Ac-FLTD-CMK is an inhibitor derived from abscisicin D (GSDMDD) with specific inhibitory effects on inflammatory caspases. ac-FLTD-CMK showed inhibitory effects on caspases-1, caspases-4 and caspases-11 with IC50s of 46.7 nM, 1.49 ?M and 329 nM, respectively. Ac-FLTD-CMK showed potency against caspases-1, caspases-4 and caspases-11, but not against apoptosis-associated caspase-3.
Smiles
CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)CCl
Molecular Formula
C26H37ClN4O8
Molecular Weight
569.05
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/ADF9CA77-86B8-446C-9957-1184B066A133/T36819
CAS Number
2376255-48-8
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1059813-01 0.02 mg (E-Coli)
Recombinant Mycobacterium ulcerans Probable transcriptional regulatory protein MUL_3246 (MUL_3246)
Ask
View Details MBS1059813-02 0.1 mg (E-Coli)
Recombinant Mycobacterium ulcerans Probable transcriptional regulatory protein MUL_3246 (MUL_3246)
Ask
View Details MBS1059813-03 0.02 mg (Yeast)
Recombinant Mycobacterium ulcerans Probable transcriptional regulatory protein MUL_3246 (MUL_3246)
Ask
View Details MBS1059813-04 0.1 mg (Yeast)
Recombinant Mycobacterium ulcerans Probable transcriptional regulatory protein MUL_3246 (MUL_3246)
Ask
View Details 
MBS1059813-05 0.02 mg (Baculovirus)
Recombinant Mycobacterium ulcerans Probable transcriptional regulatory protein MUL_3246 (MUL_3246)
Ask
View Details