Dolutegravir O-β-D-Glucuronide
Product Specifications
CAS Number
1485692-21-4
Target
Others
Related Pathways
Others
Bioactivity
Dolutegravir O-β-D-glucuronide is a metabolite of the HIV integrase inhibitor dolutegravir .1It is formed from dolutegravir primarily by the UDP-glucuronosyltransferase (UGT) isoform UGT1A1in vivobut is also metabolized by UGT1A9 in human liver and kidney microsomes and UGT1A3 in human intestinal microsomes.2,1
Smiles
[H][C@]12Cn3cc(C(=O)NCc4ccc(F)cc4F)c(=O)c(O[C@@H]4O[C@@H]([C@@H](O)[C@H](O)[C@H]4O)C(O)=O)c3C(=O)N1[C@H](C)CCO2
Molecular Formula
C26H27F2N3O11
Molecular Weight
595.509
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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