13,14-dihydro Prostaglandin E1
Product Specifications
CAS Number
19313-28-1
Target
Others, Endogenous Metabolite
Related Pathways
Metabolism, Others
Bioactivity
13,14-dihydro Prostaglandin E1 (13,14-dihydro PGE1) is a biologically active metabolite of PGE1 with comparable potency to the parent compound. It is an inhibitor of ADP-induced platelet aggregation in human PRP and washed platelets with IC50 values of 31 and 21 nM, respectively. 13,14-dihydro PGE1 is a slightly more potent inhibitor of ADP-induced human platelet aggregation than PGE1 which has an IC50 value of 40 nM. Also, 13,14-dihydro PGE1 was shown to activate adenylate cyclase in NCB-20 hybrid cells with a Kact value of 668 nM.
Smiles
CCCCC[C@H](O)CC[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O
Molecular Formula
C20H36O5
Molecular Weight
356.503
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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