Mollugin
Product Specifications
CAS Number
55481-88-4
Target
ROS|||Reactive Oxygen Species|||c-Myc|||NF-?B|||Apoptosis|||VEGFR|||HER|||JAK
Related Pathways
Tyrosine Kinase/Adaptors|||Angiogenesis|||Metabolism|||Immunology/Inflammation|||NF-?B|||JAK/STAT signaling|||Cell Cycle/Checkpoint|||Apoptosis|||Chromatin/Epigenetic|||Stem Cells
Purity
0.9987
Bioactivity
Mollugin (Rubimaillin) may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin as a candidate for a chemotherapeutic agent in OSCCs via the upregulation of the HO-1 and Nrf2 pathways and the downregulation of NF- ? B. Mollugin may be a novel therapeutic candidate for bone loss-associated disorders including osteoporosis, rheumatoid arthritis, and periodontitis. Also, it has anticancer efficacy, can modulate the HER2 pathway in HER2-overexpressing Y cells with a potential role in the treatment and prevention of human breast and ovarian Y with HER2 overexpression.
Smiles
COC(=O)c1c(O)c2ccccc2c2OC(C)(C)C=Cc12
Molecular Formula
C17H16O4
Molecular Weight
284.31
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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