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N'-Nitrosonornicotine

Product Specifications

CAS Number

80508-23-2

Target

Others, Drug Metabolite

Related Pathways

Metabolism, Others

Bioactivity

N'-Nitrosonornicotine is a tobacco-specific N-nitrosamine and carcinogen that has been found in unburned tobacco and cigarette smoke.1It induces the formation of DNA adducts in isolated rat nasal mucosa and esophagus. N'-Nitrosonornicotine induces tumor formation in rat esophagus and nasal cavity, mouse lung, forestomach, and trachea, and hamster trachea and forebrain. Urinary levels of N'-nitrosonornicotine are positively correlated with the risk of esophageal cancer in smokers.2

Smiles

O=NN1CCCC1c1cccnc1

Molecular Formula

C9H11N3O

Molecular Weight

177.207

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Frequently Asked Questions

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