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Bottromycin A2

Product Specifications

CAS Number

15005-62-6

Target

Others, Antibacterial, Antibiotic

Related Pathways

Others, Microbiology/Virology

Bioactivity

Bottromycin A2is an antibiotic originally isolated fromStreptomyces.1It blocks the binding of aminoacyl-tRNA to the A site of the 50S ribosome, inhibiting protein synthesis.2Bottromycin A2is active against clinical isolates of methicillin-resistantStaphylococcus aureus (MRSA) and vancomycin-resistantEnterococciwith MIC values of 1 and 0.5 μg/ml, respectively.

Smiles

[H][C@@]12[C@H](C)CCN1C(=O)CN=C(N[C@H](C(=O)N[C@@H]([C@@H](C)c1ccccc1)C(=O)N[C@H](CC(=O)OC)c1nccs1)C(C)(C)C)C(NC(=O)C(NC2=O)C(C)C)C(C)(C)C |w:10.10,@:52,@@:55|

Molecular Formula

C42H62N8O7S

Molecular Weight

823.07

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Frequently Asked Questions

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