FD-211
Product Specifications
CAS Number
162341-24-4
Target
Others
Related Pathways
Others
Bioactivity
FD-211 is a ? lactone originally isolated from M. lutea with anticancer activity.1 It is cytotoxic to adriamycin-susceptible P388, T-24, HeLa, A549, and HL-60 cancer cells (IC50s = 4, 0.5, 1, 1, and 0.2 ?g/ml, respectively), as well as adriamycin-resistant HL-60/ADR cells (IC50 = 0.1 ?g/ml) . FD-211 also inhibits DNA, RNA, and protein synthesis in HeLa cells (IC50 = 1.25 ?g/ml for all) .
Smiles
[H][C@@]12O[C@H](\C=C\C)[C@H](O)C=C1C(=O)O[C@H]2\C=C\C|c:9|
Molecular Formula
C13H16O4
Molecular Weight
236.267
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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