Fanotaprim
Product Specifications
CAS Number
2120282-75-7
Target
DHFR, Antifolate
Related Pathways
Metabolism, DNA Damage/DNA Repair, Cell Cycle/Checkpoint
Purity
0.981
Bioactivity
Fanotaprim is a dihydrofolate reductase (DHFR) inhibitor, suppressing the growth of T. gondii strains with a TgDHFR IC50 of 1.57 ± 0.11 nM, a hDHFR IC50 of 308 ± 71 nM, and a hDHFR to TgDHFR selectivity ratio of 196.
Smiles
COc1ncc(cn1)-c1cccc(c1)N1CCN(CC1)c1cnc(N)nc1N
Molecular Formula
C19H22N8O
Molecular Weight
378.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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