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Fanotaprim

Product Specifications

CAS Number

2120282-75-7

Target

DHFR, Antifolate

Related Pathways

Metabolism, DNA Damage/DNA Repair, Cell Cycle/Checkpoint

Purity

0.981

Bioactivity

Fanotaprim is a dihydrofolate reductase (DHFR) inhibitor, suppressing the growth of T. gondii strains with a TgDHFR IC50 of 1.57 ± 0.11 nM, a hDHFR IC50 of 308 ± 71 nM, and a hDHFR to TgDHFR selectivity ratio of 196.

Smiles

COc1ncc(cn1)-c1cccc(c1)N1CCN(CC1)c1cnc(N)nc1N

Molecular Formula

C19H22N8O

Molecular Weight

378.43

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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