Rp-8-CPT-cAMPS sodium
Product Specifications
CAS Number
221905-35-7
Target
PKA, Others
Related Pathways
Tyrosine Kinase/Adaptors, Others
Bioactivity
Rp-8-CPT-cAMP is a structural combination of the lipophilic and non-hydrolyzable cAMP analogs, 8-CPT-cyclic AMP and Rp-cyclic AMPS .[1] It functions as a site-selective inhibitor of protein kinase A (PKA) type I and II, with preference towards site A of type I and site B of type II.2 By occupying cAMP binding sites at the regulatory subunit of PKA, Rp-8-CPT-cAMP prevents the kinase holoenzyme from dissociative activation.[2], [3]
Smiles
[Na].[H][C@@]12COP(S)(=O)O[C@@]1([H])[C@@H](O)[C@@H](O2)n1c(Sc2ccc(Cl)cc2)nc2c(N)ncnc12
Molecular Formula
C16H14ClN5NaO5PS2
Molecular Weight
509.86
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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