Tucatinib hemiethanolate
Product Specifications
CAS Number
1429755-56-5
Target
EGFR, HER
Related Pathways
Angiogenesis, JAK/STAT signaling, Tyrosine Kinase/Adaptors
Purity
0.9976
Bioactivity
Tucatinib (Irbinitinib) hemiethanolate is a potent, orally active, and selective HER2 inhibitor with an IC50 of 8 nM.
Smiles
CCO.Cc1cc(Nc2ncnc3ccc(NC4=NC(C)(C)CO4)cc23)ccc1Oc1ccn2ncnc2c1.Cc1cc(Nc2ncnc3ccc(NC4=NC(C)(C)CO4)cc23)ccc1Oc1ccn2ncnc2c1
Molecular Formula
C54H54N16O5
Molecular Weight
1007.11
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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