TEI-9648
Product Specifications
CAS Number
173388-21-1
Target
Others, Vitamin
Related Pathways
Others, Metabolism
Bioactivity
TEI-9648, an analogue of Vitamin D3 Lactone, acts as a potent and specific antagonist to the vitamin D receptor (VDR) . This compound effectively blocks the genomic actions mediated by VDR and the Vitamin D responsive element (VDRE) of 1α,25 (OH) 2D3. Furthermore, TEI-9648 prevents the differentiation of HL-60 cells induced by 1α,25 (OH) 2D3, indicating its utility in bone metabolism studies[1][2].
Smiles
[H][C@@]12CC[C@H]([C@H](C)C[C@@H]3CC(=C)C(=O)O3)[C@@]1(C)CCC\C2=C/C=C1/C[C@@H](O)C[C@H](O)C1=C
Molecular Formula
C27H38O4
Molecular Weight
426.597
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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