Zorifertinib
Product Specifications
CAS Number
1626387-80-1
Target
Apoptosis, EGFR
Related Pathways
Tyrosine Kinase/Adaptors, Apoptosis, Angiogenesis, JAK/STAT signaling
Purity
0.9936
Bioactivity
Zorifertinib (AZD3759) is an orally active, effective and central nervous system-penetrant EGFR inhibitor. The IC50 values were 0.2, 0.3 and 0.2 nM for EGFR L858R mutant, TK wild-type, and Exon 19Del enzymes, respectively.
Smiles
N(C=1C2=C(C=C(OC)C(OC(=O)N3[C@H](C)CN(C)CC3)=C2)N=CN1)C4=C(F)C(Cl)=CC=C4
Molecular Formula
C22H23ClFN5O3
Molecular Weight
459.9
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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