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NHWD-870

Product Specifications

CAS Number

2115742-03-3

Target

Apoptosis, Epigenetic Reader Domain

Related Pathways

Apoptosis, Chromatin/Epigenetic

Bioactivity

NHWD-870 is an effective and selective inhibitor of BET family bromodomain only binding to BRD2, BRD3, BRD4 (IC50 = 2.7 nM), and BRDT. NHWD-870 exhibits potent anti-tumor efficacies and suppresses cancer cell-macrophage interaction through the increase of tumor apoptosis and inhibition of tumor proliferation.

Smiles

Cc1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc3n(C)ncc3cc21

Molecular Formula

C29H29N7O

Molecular Weight

491.59

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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