NHWD-870
Product Specifications
CAS Number
2115742-03-3
Target
Apoptosis|||Epigenetic Reader Domain
Related Pathways
Apoptosis|||Chromatin/Epigenetic
Bioactivity
NHWD-870 is an effective and selective inhibitor of BET family bromodomain only binding to BRD2, BRD3, BRD4 (IC50 = 2.7 nM), and BRDT. NHWD-870 exhibits potent anti-tumor efficacies and suppresses cancer cell-macrophage interaction through the increase of tumor apoptosis and inhibition of tumor proliferation.
Smiles
Cc1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc3n(C)ncc3cc21
Molecular Formula
C29H29N7O
Molecular Weight
491.59
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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