BMS-1
Product Specifications
CAS Number
1675201-83-8
Target
PD-1/PD-L1|||Apoptosis
Related Pathways
Cell Cycle/Checkpoint|||Apoptosis|||Immunology/Inflammation
Purity
0.9986
Bioactivity
BMS-1 (PD-1/PD-L1 inhibitor 1) is an inhibitor of the PD1-PD-L1 protein-protein interaction. It also acts as an immunomodulator. Programmed death ligand 1 (PD-L1) is a protein in humans that is encoded by the CD274 gene and the upregulation of PD-L1 allows Ys to evade the host immune system. High tumor expression of PD-L1 was associated with increased tumor aggressiveness and a 4.5-fold increased risk of death.
Smiles
COc1cc(OCc2cccc(c2C)-c2ccccc2)cc(OC)c1CN1CCCC[C@H]1C(O)=O
Molecular Formula
C29H33NO5
Molecular Weight
475.58
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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