APY29

Product Specifications

CAS Number

1216665-49-4

Target

IRE1

Related Pathways

Cell Cycle/Checkpoint

Purity

0.9846

Bioactivity

APY29 is an allosteric modulator of IRE1?; inhibits IRE1? autophosphorylation (IC50 = 280 nM) and activates IRE1? RNase activity.

Smiles

C1CC1c1cc(Nc2ccnc(Nc3ccc4nc[nH]c4c3)n2)n[nH]1

Molecular Formula

C17H16N8

Molecular Weight

332.36

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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