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Nocardamine

Product Specifications

CAS Number

26605-16-3

Target

Others

Related Pathways

Others

Bioactivity

Nocardamine is a ferrioxamine siderophore that has been found inStreptomycesand has diverse biological activities.1,2,3,4It chelates iron in a chrome azurol S assay (IC50= 9.9 μM) .1Nocardamine inhibitsM. smegmatisandM. bovisbiofilm formation (MIC = 10 μM for both), an effect that can be reversed by iron.2It is cytotoxic to T47D, SK-MEL-5, SK-MEL-28, and RPMI-7951 cancer cells (IC50s = 6, 18, 12, and 14 μM, respectively) .3Nocardamine also induces morphological changes in BM-N4 insect cells.4

Smiles

ON1CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC1=O

Molecular Formula

C27H48N6O9

Molecular Weight

600.7

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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