Ternatin
Product Specifications
CAS Number
148619-41-4
Target
Others
Related Pathways
Others
Bioactivity
Ternatin is a cyclic heptapeptide first isolated from the mushroom C. versicolor that has been shown to have cytotoxic and anti-adipogenic effects in vitro. It inhibits adipogenesis with an IC50 value of 27 nM and becomes cytotoxic to 3T3-L1 mouse adipocytes at 10-fold higher concentrations. Ternatin is reported to inhibit HCT116 cell proliferation with an IC50 value of 71 nM. Note that this metabolite should not be confused with the plant flavonoid of the same name.
Smiles
[H][C@@]1(NC(=O)[C@@H](C)N(C)C(=O)[C@H](C)N(C)C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C)N(C)C(=O)[C@]([H])(NC1=O)[C@H](C)CC)[C@H](O)C(C)C
Molecular Formula
C37H67N7O8
Molecular Weight
737.984
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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