CAY10770
Product Specifications
CAS Number
2428734-45-4
Target
Cytochromes P450, Others
Related Pathways
Metabolism, Others
Bioactivity
CAY10770 is an inhibitor of the cytochrome P450 (CYP) isoform CYP4Z1 (IC50= 5.9 μM) .1It is selective for CYP4Z1 over CYP4A11, CYP4F2, CYP4F3a, CYP4F3b (IC50s = 187-282 μM) but does inhibit CYP4F8 and CYP4F12 (IC50s = 167 and 91 μM, respectively) . CAY10770 (3 μM) inhibits the production of 14 (15) -EET, 19-HETE, and 14 (15) -DiHET by 83, 86, and 80%, respectively, in T47D breast cancer cells expressing CYP4Z1.
Smiles
N(CCCCCCCC(O)=O)N1C=2C(N=N1)=CC=CC2
Molecular Formula
C14H20N4O2
Molecular Weight
276.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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